| Injury | Disease | Nutrition | Poison |
| Symptoms | Surgery | Test | Special Topic |
| 1 | 2 | 5 | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X |
|
Serum phenylalanine screening |
| Definition: |
| Serum phenylalanine screening is a test for the disease phenylketonuria (PKU). The test detects abnormally high levels of phenylalanine.
|
| Alternative Names: |
| Phenylalanine; Phenylalanine - serum |
| How the test is performed: |
An area of the infant's skin, usually the heel, is cleansed with antiseptic and punctured with a sharp needle or a lancet. Three drops of blood are placed in three separate test circles on a piece of paper. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding. The test paper is taken to the laboratory where it is mixed with a type of bacteria that needs phenylalanine to grow, and another substance that inhibits phenylalanine from reacting with anything else. |
| How to prepare for the test: |
For help preparing your baby for the test, see the following topic:
|
| How the test will feel: |
| When the needle is inserted to draw blood, some infants feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
|
| Why the test is performed: |
This test is performed on infants to screen for phenylketonuria (PKU). This disease is caused by a deficiency of the enzyme needed to breakdown the amino acid phenylalanine. If PKU is not detected early, an affected infant will become mentally retarded as the amino acid level builds up. However, if it is detected early, the severe side effects of PKU may be avoided through diet modification. Therefore, even though the condition is relatively rare, most newborns are screened. |
| Normal Values: |
| A normal test results in no bacteria growth. This indicates that phenylalanine levels are normal.
|
| What abnormal results mean: |
| Bacteria growth indicates that phenylalanine levels in the infant's blood are too high. PKU is a possibility and further testing will be performed.
|
| What the risks are: |
The risks of having blood drawn are slight, but include:
|
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2004 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
