The healthy pancreas is obtained from a donor who has suffered brain-death, but remains on life-support. Numerous criteria must be met to assess the donor's suitability. In additon to insulin, the pancreas produces other secretions, such as digestive enzymes, which drain through the pancreatic duct into the duodenum. Therefore, a portion of the duodenum is removed with the donor pancreas. The healthy pancreas is transported in a cooled solution that preserves the organ for up to 20 hours. The patient's diseased pancreas is not removed during the operation. The donor pancreas is usually inserted in the right lower portion of the patient's abdomen and attachments are made to the patient's blood vessels. The donor duodenum is attached to the patient's intestine or bladder to drain pancreatic secretions. The operation may be done at the same time as a kidney transplant in diabetic patients with kidney disease.
|