Antihypertensives -Thiazide and related diuretics

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Antihypertensives -Thiazide and related diuretics

Definition:

This is poisoning from a thiazide or related diuretic.

Poisonous Ingredient:

any of the following

bendroflumethiazide
benzthiazide
chlorothiazide
chlorthalidone
hydrochlorothiazide (HCTZ)
hydroflumethiazide
indapamide
methyclothiazide
metolazone
polythiazide
quinethazone
trichlormethiazide

Note: This list may not be all inclusive.

Where Found:

bendroflumethiazide (Naturetin)
benzthiazide (Exna)
chlorothiazide (Diuril, Diurigen)
chlorthalidone (Thalitone, Hygroton
hydrochlorothiazide (Esidrix, HydroDIURIL, Hydro-Par, Oretic)
hydroflumethiazide (Diucardin, Saluron)
indapamide (Lozol)
methyclothiazide (Enduron, Aquatensen)
metolazone (Zaroxolyn, Diulo)
polythiazide (Renese)
quinethazone (Hydromox)
trichlormethiazide (Metahydrin, Naqua, Diurese)

Note: This list may not be all inclusive.

Symptoms:

body as a whole
- dizziness
- drowsiness
- fainting
- confusion
- weakness
- coma
- muscle cramps
- frequent urination
- pale-colored urine
- fever
respiratory
- slow breathing
eyes, ears, nose, and throat
- photosensitivity
- color vision abnormalities (yellow tinge)
skin
- rash
- yellow skin
gastrointestinal
- nausea and/or vomiting
heart and blood vessels
- low blood pressure

Home Treatment:

Do not induce vomiting unless instructed to do so by Poison Control or by a physician.

Before Calling Emergency:

Determine the following information:

the patient's age, weight, and condition
the name of the product (ingredients and strengths if known)
the time it was swallowed
the amount swallowed

Poison Control, or a local emergency number:

They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What to expect at the emergency room:

Some or all of the following procedures may be performed:

induce vomiting
administer activated charcoal
monitor vital signs ( blood pressure, pulse, and so forth)
monitor EKG (monitors heart function)
blood samples drawn to determine serum electrolyte levels
correction of electrolyte imbalances and fluid imbalances

Expectations (prognosis):

Patients usually respond well to treatment. Serious symptoms and death are unlikely.

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